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Contents: In This Site (2025)

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Finding answers on the web can be challenging, often requiring multiple attempts to obtain relevant results. While AI tools like ChatGPT, Perplexity, Grok, Deepseek, and Google Gemini strive to provide helpful responses, there may be instances where they cannot provide specific answers to your questions. Please remember this site has a search function (upper right) so that you can search for the content you are looking for. One Day MD isn’t about us—it’s about you. Can you be your own health advocate? You know your body best. While your doctor isn’t always there, you have constant access to resources like the internet, Google, and ChatGPT. It’s time to take control of your health. Learning from online resources won’t make you an MD overnight, but it’s a powerful first step toward better health for you and those you care about. The internet now provides access to global information and connections, empowering you to build a community or join a movement with ease. That said, you must als...

Fact Check: Can Ivermectin and Fenbendazole Help Treat Cancer?

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Ivermectin and fenbendazole, originally developed as antiparasitic drugs, are sparking hope in the fight against cancer, fueled by inspiring stories like those shared by actor  Mel Gibson on The Joe Rogan Experience , where he celebrated friends’ remarkable recoveries. While these medications aren’t yet standard cancer treatments, early research is uncovering exciting potential. Scientists are encouraged by promising lab studies and are calling for more clinical trials to confirm their effectiveness and ensure safe use in humans, paving the way for innovative, accessible therapies that could transform lives. Introduction and Context According to a January 22, 2025 fact-check article by AFP: "The anti-parasitic drugs ivermectin and fenbendazole are not currently recommended for cancer, but posts spread across social media touting the medications after actor  Mel Gibson claimed on the Joe Rogan Experience  that they cured his friends' cases of the disease. Oncology ex...

Anti-Parasitic Drugs in Cancer Therapy: Analyzing drugs like ivermectin, fenbendazole and mebendazole for their potential to disrupt cancer cell signaling or enhance chemotherapy

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Anti-parasitic drugs such as ivermectin, fenbendazole, and mebendazole have shown promising potential in cancer therapy by disrupting cancer cell signaling and enhancing chemotherapy efficacy through multiple mechanisms. Fenbendazole Fenbendazole, a benzimidazole anthelmintic, exhibits several anti-cancer effects: Microtubule disruption:  Fenbendazole acts as a moderate microtubule destabilizing agent, impairing microtubule polymerization which is critical for cancer cell division 4 6 . Metabolic interference:  It inhibits glucose uptake by downregulating GLUT1 transporters and hexokinase II (HKII), key components of glycolysis, thereby starving cancer cells of energy and reversing drug resistance 1 4 6 . Activation of p53 pathway:  Fenbendazole induces mitochondrial translocation of p53, promoting apoptosis and cell cycle arrest at the G2/M phase 1 2 4 . Induction of multiple cell death pathways:  It triggers apoptosis, necrosis, autophagy, and ferroptosis, includin...